PIPERAZINE-1,2,4-TRICARBOXYLIC ACID 1-TERT-BUTYL ESTER 4-(9H-FLUOREN-9-YLMETHYL) ESTER
1-Boc-4-Fmoc-2-piperazinecarboxylic acid
CAS: 218278-58-1
Molecular Formula: C25H28N2O6
PIPERAZINE-1,2,4-TRICARBOXYLIC ACID 1-TERT-BUTYL ESTER 4-(9H-FLUOREN-9-YLMETHYL) ESTER - Names and Identifiers
PIPERAZINE-1,2,4-TRICARBOXYLIC ACID 1-TERT-BUTYL ESTER 4-(9H-FLUOREN-9-YLMETHYL) ESTER - Physico-chemical Properties
| Molecular Formula | C25H28N2O6 |
| Molar Mass | 452.5 |
| Density | 1.292±0.06 g/cm3(Predicted) |
| Melting Point | 156 °C |
| Boling Point | 624.4±55.0 °C(Predicted) |
| Flash Point | 331.4°C |
| Vapor Presure | 1.88E-16mmHg at 25°C |
| pKa | 3.68±0.20(Predicted) |
| Storage Condition | 2-8°C |
PIPERAZINE-1,2,4-TRICARBOXYLIC ACID 1-TERT-BUTYL ESTER 4-(9H-FLUOREN-9-YLMETHYL) ESTER - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S22 - Do not breathe dust. |
PIPERAZINE-1,2,4-TRICARBOXYLIC ACID 1-TERT-BUTYL ESTER 4-(9H-FLUOREN-9-YLMETHYL) ESTER - Introduction
acid (acid) is an organic compound. Its chemical formula is c₂ H, and its molecular weight is 421.48g/mol. It is a white crystalline or powdery solid and is soluble in some organic solvents such as dimethylsulfite (DMSO) and dimethylformamide (DMF).
This compound is commonly used in the reaction of protecting groups in organic synthesis. It can be used as an N-protecting group to protect some amino or imine compounds to prevent them from undergoing non-selective functional group conversion in the reaction. In addition, it can also be used to prepare different drugs and bioactive molecular intermediates.
Preparation of acid Generally, starting from 4-Fluoroaniline, N-(4-Fluorophenyl)piperazine(N-4-fluorophenyl piperazine) is first prepared. The target product is then obtained by Boc protection of piperazine followed by Fmoc protection at the 1-position. During the synthesis, attention should be paid to the operating temperature and reaction conditions to ensure high yield and purity.
Regarding safety information, acid is a chemical and should be handled in accordance with relevant laboratory safety procedures. It may be irritating and damaging to the eyes, skin and respiratory system, so appropriate protective measures, such as wearing protective glasses, gloves and respiratory protective equipment, should be taken. During use, avoid inhaling its dust or solution and avoid skin contact. In case of accidental contact, rinse immediately with plenty of water and seek medical help if necessary.
This compound is commonly used in the reaction of protecting groups in organic synthesis. It can be used as an N-protecting group to protect some amino or imine compounds to prevent them from undergoing non-selective functional group conversion in the reaction. In addition, it can also be used to prepare different drugs and bioactive molecular intermediates.
Preparation of acid Generally, starting from 4-Fluoroaniline, N-(4-Fluorophenyl)piperazine(N-4-fluorophenyl piperazine) is first prepared. The target product is then obtained by Boc protection of piperazine followed by Fmoc protection at the 1-position. During the synthesis, attention should be paid to the operating temperature and reaction conditions to ensure high yield and purity.
Regarding safety information, acid is a chemical and should be handled in accordance with relevant laboratory safety procedures. It may be irritating and damaging to the eyes, skin and respiratory system, so appropriate protective measures, such as wearing protective glasses, gloves and respiratory protective equipment, should be taken. During use, avoid inhaling its dust or solution and avoid skin contact. In case of accidental contact, rinse immediately with plenty of water and seek medical help if necessary.
Last Update：2024-04-09 20:49:11
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Product Name: 1-Boc-4-Fmoc-2-piperazinecarboxylic acid Visit Supplier Webpage Request for quotation
CAS: 218278-58-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 218278-58-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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